Tesco is submitting plans for a 700,000 sq ft distribution warehouse on the 58-acre former Courage Brewery site at Worton Grange in Whitley, Reading, Berkshire.
The site overlooks the motorway just off the A33 and the M4 junction 11. And will be constructed to the highest environmental standards.
Tesco subsidiary Spen Hill Developments intends to put in a planning application to Reading and Wokingham councils imminently.
The company hopes to open the new depot within a year if all goes to plan.
It says 1,000 jobs will be created at the depot, including 100 managerial jobs and 150 construction jobs.
There will also be jobs for warehouse staff, drivers, supervisors, catering and maintenance, with shifts available over a 24-hour period.